Wednesday, October 18, 2023


The PFAS panic continues

See below. As usual, only the weakest effects were oberved, consistent with no stable real effects. The study had its amusing side. Rather a lot of substances correlated with the alleged effect, including a form of acetic acid. Acetic acid is the key ingredient of vinegar. So might vinegar delay puberty onset in girls? Could be on these figures!

Exposure to Perfluoroalkyl Substances and Associations with Pubertal Onset and Serum Reproductive Hormones in a Longitudinal Study of Young Girls in Greater Cincinnati and the San Francisco Bay Area

Susan M. Pinney et al.

Abstract

Background:
Per- and polyfluoroalkyl substances (PFAS), endocrine disrupting chemicals with worldwide exposure, cause changes in mammary gland development in rodents. A few human studies report delay in pubertal events with increasing perfluorooctanoic acid (PFOA) exposure, but to our knowledge none have examined reproductive hormone levels at thelarche.

Methods:
In a cohort of Greater Cincinnati (GC) and San Francisco Bay Area (SFBA) girls recruited at 6–8 years of age, clinical examinations were conducted annually or semiannually with sequential Tanner staging. PFAS concentrations were measured in the first serum sample of 704 girls. In 304 GC girls, estradiol (E2), testosterone (T), and dihydroepiandrosterone sulfate (DHEAS) were measured in serum at four time points around puberty. Relationships between PFAS and age at thelarche, pubarche, and menarche were analyzed using survival and structural equation models. The association between PFAS and reproductive hormones was assessed using linear regression models.

Results:

Median PFOA serum concentrations in GC were higher than in the U.S. population. In multivariable Cox proportional hazard models [adjusted for race, body mass index (BMI)], increasing serum log-transformed PFOA was associated with a delay in pubarche [hazard ratio equals 0.83hazard ratio (HR)=0.83
; 95% CI: 0.70, 0.99] and menarche (hazard ratio equals 0.04HR=0.04; 95% CI: 0.01, 0.25).

Structural equation models indicated a triangular relationship between PFOA, BMI percentile, and the age at the pubertal milestone. Increased PFOA had a statistically significant direct effect of delay on all three milestones, as did BMI. Perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDeA), and 2-(N
-methyl-perfluorooctane sulfonamido) acetic acid (Me-PFOSA-AcOH) also were associated with later thelarche, and Me-PFOSA-AcOH also with later pubarche. PFOA was inversely associated with DHEAS (E1), and T concentrations at 6 months prior to puberty.

Conclusions:
PFAS may delay pubertal onset through the intervening effects on BMI and reproductive hormones. The decreases in DHEAS and E1 associated with PFOA represent biological biomarkers of effect consistent with the delay in onset of puberty.

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India's top court refuses to legalise same-sex marriage in landmark verdict

India's top court said today it cannot legalise same-sex marriages, with the chief justice of the country saying making such a law is the domain of parliament.

A five-judge bench headed by the Chief Justice of India, D.Y. Chandrachud, heard arguments in the case between April and May this year and pronounced its verdict today.

Chandrachud said there was a degree of 'agreement and disagreement on how far we have to go' on same-sex marriages as he began reading his order.

Two of the other four judges agreed with Chandrachud on the court not legalising same-sex marriages, making it a majority. Two other judges are yet to speak.

The news was greeted with disappointment by those who had gathered outside the court in the hopes of celebrating India becoming the second Asian jurisdiction outside Taiwan to legalise same-sex marriages.

The petitioners had said validating same-sex marriage would help them access some of the legal benefits of matrimony, including adoption, insurance and inheritance.

Advocates representing nearly two dozen petitioners said it was time for India to treat the country's LGBTQ community as equal citizens under its constitution.

But the verdict said that the charter did not guarantee a fundamental right to marry that would extend to same-sex couples under existing law.

'It lies within the domain of parliament and state legislatures to determine the law on marriage,' Chandrachud said during his verdict.

Chandrachud added that India still had a duty to acknowledge same-sex relationships and protect those in them from discrimination.

'Our ability to feel love and affection for one another makes us feel human,' he said from the bench. 'This court has recognised that equality demands that queer unions and queer persons are not discriminated against.'

The court ruling comes five years after a historic 2018 judgement when the Supreme Court scrapped a colonial-era ban on gay sex.

Only Taiwan and Nepal allow same-sex unions in Asia, where largely conservative values still dominate politics and society.

But the Hindu nationalist government of Prime Minister Narendra Modi has staunchly opposed same-sex marriage, calling the petitions 'urban elitist views' and stating that parliament is the right platform to debate and legislate on the matter.

'Any interference... would cause a complete havoc with the delicate balance of personal laws in the country and in accepted societal values', the government said in its submission.

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Father Whose Son Had Transgender Surgery Despite Court Order Issues Dire Warning About Parental Rights

A California father has urged a court to find his ex-wife, her lawyer, his son’s lawyer, and a hospital in contempt of court after they went around a court order stipulating that his son would not receive transgender-related surgery unless the father approved it.

“This is not an accident,” Ted Hudacko, the father in question, told The Daily Signal in a phone interview last week. “This was intentionally done.”

He also warned that two of the figures in his story—the judge who revoked his visitation rights and the lawyer who represents the University of California, San Francisco (where the surgery took place), are pro-transgender activists who train custody attorneys to undermine the parental rights of “non-affirming” parents (parents who refuse to affirm their child’s decision to identify as another gender).

Hudacko exclusively shared the four contempt of court filings with The Daily Signal. The filings claim that his ex-wife, Christine Hudacko; her attorney, Nathaniel Bigger; his son’s attorney, Daniel Harkins; and the university violated an August 2020 order from California Superior Court Judge Joni Hiramoto.

Hiramoto had granted Christine Hudacko full custody of the son, Drew Hudacko, but restricted any transgender medical interventions Drew might receive to non-surgical alterations. (The son’s name has been changed in this article to preserve his anonymity.)

“Citees Christine Hudacko; her attorney, Nathaniel Bigger; minor’s counsel, Daniel Harkins; and University of California, San Francisco should each be held in contempt because each knew about, then collectively conspired to willfully disobey what is herein termed the ‘no surgery injunction,’ i.e. Judge Hiramoto’s valid August 26, 2020, court order explicitly prohibiting ‘any gender identity-related surgery’ upon the minor child,” the motions read.

Ted Hudacko’s motions note that the case “centers around the parties’ disagreement over whether it was or was not in the minor child’s best interest to undergo gender identity-related medical procedures,” with Christine Hudacko supporting a medical “transition” and Ted Hudacko opposing it.

The father “will establish that the law will hold non-parties liable for contempt when they know of the order and assist in its violation,” the filings read.

Ted Hudacko claims that “each of the citees was aware of the no surgery injunction, and that they individually and collectively decided to cause the minor child to undergo the gender identity related medical procedure of histrelin (brand name ‘Supprelin’) subcutaneous implant (‘Supprelin implant’), a surgery under the acceptable statutory definition, and by UCSF’s [University of California, San Francisco’s] own statements.”

The filings cite the Aug. 26 order’s two provisions on the issue:

[Drew] shall be permitted to pursue the services provided by UCSF as to [Drew]’s gender identity, and shall be permitted to commence hormone therapy, if recommended by UCSF.

[Drew] will not be permitted to undergo any gender identity related surgery until they are 18 years of age, absent a written agreement by both parties, Christine Hudacko and Edward Hudacko, or an order of the court.

On Feb. 17, 2021, Christine Hudacko took 16-year-old Drew to the University of California, San Francisco Child and Adolescent Gender Center. Doctors discussed experimental medical interventions often referred to as “puberty blockers.” They presented Drew and his mother four different options, only one of which involved any surgery. Drew and his mother selected that option, and the boy went under the knife on Aug. 4, 2021.

Ted Hudacko, who had a right to know about his son’s medical progress, did not learn about the surgery until Oct. 18, 2021, when his ex-wife notified him. He told The Daily Signal that he recalled wondering, “Why is there a $209,820.34 charge on my insurance?”

He cited a June 8, 2021, progress note from the court mentioning that the father is “not supportive” and he pushed back on the idea that he did not support his son.

“No, I’m supportive because I want to protect my child’s health. I don’t want to subject him to being a guinea pig in an experiment,” Ted Hudacko said. He mentioned a growing list of doctors in the U.S. and elsewhere who warn that medical interventions aimed at making a male appear female or vice versa—often euphemistically termed “gender-affirming care”—are experimental and not advisable.

“They easily could have avoided violating the court order,” the father added. “It’s not like this was a lifesaving surgery. This was completely elective, and they had nonsurgical options available, but they didn’t choose the nonsurgical options.”

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Hundreds Killed by Islamic Jihad After Misfire Causes Explosion at Gaza City Hospital

Following a blast at a hospital in Gaza City on Tuesday, Hamas immediately claimed that an Israel Defense Forces strike was to blame — but the evidence does not support such claims from Hamas officials pretending to be impartial government ministers inside the Gaza Strip. In fact, the evidence disproves what Hamas — and many of its sympathizers in the media and politics — have said.

Instead of what Hamas rushed to claim, it appears the attempt to blame Israeli forces and further demonize Israel and its people is nothing more than scrambling to draw attention away from the mass-casualty event that was, in fact, the result of a misfired Hamas or another Iran-backed terrorist's rocket and, potentially simultaneously, an attempt to cover up the fact that Hamas was again using a hospital to house terrorist infrastructure and weapons stockpiles.

In addition, Al Jazeera unwittingly broadcast live video of the terrorist rocket misfiring and blowing up the hospital in Gaza City.

The blast occurred just minutes after a large barrage of Hamas rockets were fired toward Tel Aviv and Hamas reportedly announced that they were in the process of launching their "most robust weapons" at Haifa just before the hospital explosion — but no such weapon reached Haifa.

After an initial investigation on Tuesday, the IDF said they have evidence showing the hospital explosion was in fact caused by a botched Hamas rocket launch intended for Israeli civilians, potentially from the surveillance drones swarming the skies. What's more, IDF was not active in the area of the explosion at the time it occurred.

Even pro-Gaza outlets have reported that the hospital was struck by a misfired rocket which also set off more terrorist weapons stored in the hospital.

Subsequent investigation by the IDF led them to the conclusion that the explosion was caused by a misfired rocket launched by Islamic Jihad, a frequent coordinating partner of Hamas:

It's no secret that terrorist rockets launched from the Gaza Strip — often cannibalized from street signposts, sewer pipes, and other tubes intended for other peaceful uses — often misfire and land inside the Gaza Strip.

Also worth noting is the fact that Israel called for the evacuation of civilians from hospitals and other locations in the northern Gaza Strip on Friday — something Hamas worked to prevent by blocking evacuation routes and telling residents to stay put in order for the Iran-backed terrorists to maintain the presence of human shields.

As Fox News Channel's Trey Yingst pointed out, every claim from Hamas and subsequent reporting of those claims must be scrutinized and verified — but that hasn't stopped pro-Hamas media outlets from quickly parroting their anti-Israel narrative.

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My other blogs. Main ones below:

http://dissectleft.blogspot.com (DISSECTING LEFTISM)

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

http://jonjayray.com/blogall.html More blogs

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