Sunday, April 21, 2024
A study found that chemicals produced when eating junk food raised cancer risk
See below for a less sensationalist report of the research
Bah! Humbug! The researchers have NO data on junk food consumption. Their apparent link to food seems to be that levels of harm are linked to high glucose intake in some people. But glucose is not specific to junk food. Common table sugar is a compound of glucose and fructose. So if the results mean anything they mean that eating a lot of sweet things of any kind is bad for you if you have certain rare genetic predispositons. That is the sum total of what they apparently show. It tells you NOTHING about junk foods, whatever they may be. If you take it all seriously, people with certain rare genetics should avoid putting sugar in their coffee! Big problem!
Scientists believe they have uncovered a missing link between how eating junk food increases the risk of cancer.
A study in Singapore looked at the effect of methylglyoxal, a compound released when the body breaks down sugary and fatty foods, on a gene that helps fight off tumors.
In a first, the academics found that methylglyoxal was able to temporarily shut off the BRCA2 gene's ability to protect against cancer forming and growing.
Doctors have known for decades that eating junk food is linked to a much higher risk of cancer, even if the person is not obese, but the exact mechanism is still being understood.
It could, at least in part, explain why cancers among young, ostensibly healthy Americans are becoming so prevalent, particularly tumors in the colon.
The team also noted that the study contradicts a longstanding theory called the knudson's 'two-hit' paradigm, which said that genes like BRCA2 must be completely inactive in the body to raise cancer risk.
These genes are meant to help protect the body against cancer, though patients who inherit faulty copies from their parents have been shown to have an increased risk of certain cancers, such as breast and pancreatic.
Dr Ashok Venkitaraman, study author and director of the National University of Singapore's Centre for Cancer Research, told Medical News Today: '[M]ethylglyoxal triggers the destruction of BRCA2 protein, reducing its levels in cells.'
'This effect is temporary, but can last long enough to inhibit the tumor-preventing function of BRCA2.'
Is THIS what's causing mystery rise in colon cancers among young people? Study points to bacteria in the gut linked to processed food and lack of fiber
Scientists say they may be one step closer to understanding what's driving a mystery rise in colon cancer in young people.
He noted that repeated exposure, such as through eating processed foods and red meat, among others, would increase the amount of damage to genes like BRCA2.'
The team looked at the effect of methylglyoxal on cells from people who had inherited a faulty copy of BRCA2 and were therefore more likely to develop cancer.
They found that methylglyoxal exposure disabled tumor suppression.
'It is well documented that some individuals are at a high risk of developing breast, ovarian, pancreatic or other cancers because they inherit a faulty copy of the cancer-preventing gene — BRCA2 — from their parents,' Dr Venkitaraman said.
'Our recent findings show that cells from such individuals are particularly sensitive to the effects of methylglyoxal, which is a chemical produced when our cells break down glucose to create energy.
'We find that methylglyoxal inhibits the tumor-preventing function of BRCA2, eventually causing faults in our DNA that are early warning signs of cancer development.'
Additionally, Dr Venkitaraman noted that high levels of methylglyoxal are common in people with diabetes and prediabetes.
'Our latest findings show that methylglyoxal can temporarily inactivate such cancer-preventing genes, suggesting that repeated episodes of poor diet or uncontrolled diabetes can "add up" over time to increase cancer risk,' he said.
However, the team cautioned that since the study was carried out in cells rather than people, more research is needed on the topic.
The research adds to a long list of studies suggesting that diet could have an impact on cancer risk, particularly colorectal cancer.
Research from the Cleveland Clinic, for example, found that people under 50 who ate diets rich in red meat and sugar had lower levels of the compound citrate, which is created when the body converts food into energy and has been shown to inhibit tumor growth.
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Only one man can stop the world plunging into full-scale war
The article below from just two days ago by Geraldine Brooks is an amusing example of journalistic "wisdom". She forgot that there were two sides to the conflict so was proved wrong when the "other" side backed down.
It was actually a very common fear that an Israeli attack on Iran would ignite WWIII but Bibi's judgment was proven correct when nothing in fact happened when he retaliated against the Iranians. It is in fact very reassuring that the Prime Minister of Israel was the one with the best judgment.
I was talking to my son about this matter this morning and he made the good point that Trump would have handled the matter better. He suggested that, like Biden, Trump would have supported Israel but that he would have done so in a clearer, more decisive and simpler way. I think that is true. Fortunately only one wise man was needed - Netanyhu. Alarmists are still hollering but the game seems to be basically over for now
With all the blood and terror since last October, it is easy to forget that it took five back-to-back elections to put Bibi Netanyahu in the position he now occupies: the leader whose next decision might plunge his region, and maybe the world, into full-scale war.
This power rests in the hands of a man who, at home, has become widely despised, with only 15 per cent of Israelis now saying they support him.
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Scotland Presses ‘Pause’ on Puberty Blockers, Hormone Drugs for Children
Following publication of a damning report on the dangers of gender transition procedures for children, Scotland officially is halting the prescription of puberty blockers and hormone drugs to minors.
Scotland’s sole gender clinic for minors, Glasgow-based Sandyford Sexual Health Service, announced Thursday that it no longer would refer children under 18 to pediatric endocrinology to be prescribed puberty blockers or hormone drugs.
Earlier this month, the U.K. government published The Cass Review, a much-anticipated report of nearly 400 pages compiled by an esteemed pediatrician, Dr. Hilary Cass, on gender transition procedures for children. Cass worked on the report for four years.
“The reality is that we have no good evidence on the long-term outcomes of interventions to manage gender-related distress,” the report declares. “This is an area of remarkably weak evidence.”
Sandyford Sexual Health Service announced:.
This service update follows research from NHS [National Health Service] England and the publication of The Cass Review while we work with the Scottish government to engage in research with NHS England that will generate evidence of safety and long-term impact for therapies. While this pause is in place, we will continue to give anyone who is referred into the Young People Gender Service the psychological support that they require while we review the pathways in line with the findings.
The decision by Sandyford Sexual Health Service to “pause” prescriptions of puberty blockers and hormone drugs to children is in line with new guidance from National Health Service Greater Glasgow and Clyde.
“On clinical advice, both NHS Greater Glasgow and Clyde and NHS Lothian deferred starting new patients on these treatments in mid-March 2024 in response to the position taken by NHS England and while the publication of The Cass Review was awaited,” National Health Service Greater Glasgow and Clyde said in a written statement. “Following the publication of The Cass Review and having also received the support of the chief medical officer for Scotland, Sir Gregor Smith, the health boards formally paused treatment.”
Last month, NHS England formally halted prescribing puberty blockers and hormone drugs to children, explaining: “Puberty blockers … are not available to children and young people for gender incongruence or gender dysphoria because there is not enough evidence of safety and clinical effectiveness.”
NHS England warned that hormone drugs “cause some irreversible changes” and “may cause temporary or even permanent infertility.” The agency further noted: “There is some uncertainty about the risks of long-term cross-sex hormone treatment.”
Instead of such prescriptions, NHS England explained that children diagnosed with gender dysphoria will have a range of psychological therapies available to them, including family therapy, individual child psychotherapy, parental support, or counseling, and “regular reviews to monitor gender identity development.”
NHS England explained its new guidance by saying: “Most treatments offered at this stage are psychological rather than medical. This is because in many cases gender variant behaviour or feelings disappear as children reach puberty.”
The groundbreaking report from Bass found that gender transition procedures for children are largely based on biased and even low-quality research.
Additionally, the report found that there is “no evidence” that gender transition procedures prevent or reduce the risk of suicide, despite the common claims of many gender transition advocates; the prescription of puberty blockers and hormone drugs to minors may be dangerous; the majority of children diagnosed with gender dysphoria suffer from a host of often-neglected psychological co-morbidities; and the practice of gender transition procedures has been largely guided by “toxic” debate and discourse.
As evidenced by Scotland’s change of course on puberty blockers and hormone drugs, The Cass Review is already bringing about what U.K. officials are calling a “fundamental change” in the gender transition industry.
In the course of compiling her report, Cass investigated the Gender Identity Development Service at the Tavistock clinic in London. Her findings led the pediatrician to recommend that the government shut down the clinic immediately, almost two years before her final report was due.
In particular, Cass was disturbed by Tavistock staff’s trend of placing children as young as 10 on regimens of puberty blockers or hormone drugs with little or no psychological oversight, sometimes after as few as three counseling sessions. Cass noted with alarm that about 96% of children referred to Tavistock were prescribed puberty blockers.
“We echo the views of Dr. Hilary Cass that toxicity around public debate is impacting the lives of young people seeking the care of our service and does not serve the teams working hard to care and support them,” Dr. Emelia Creighton, public health director for National Health Service Greater Glasgow and Clyde, said in a written statement.
“The findings informing the Cass Review are important, and we have reviewed the impact on our clinical pathways,” Creighton said. “The next step from here is to work with the Scottish government and academic partners to generate evidence that enables us to deliver safe care for our patients.”
NHS Lothian’s executive medical director, Tracey Gillies, said: “The Cass Review is a significant piece of work into how the NHS can better support children and young people who present with gender dysphoria. Patient safety must always be our priority, and it is right that we pause this treatment to allow more research to be carried out.”
Meanwhile, U.S. health officials have continued promoting gender transition procedures—including puberty blockers and hormone drugs—for children. Last year, a report named the U.S. an “outlier” in the field of protecting children from harmful gender transition procedures after France, Sweden, Finland, Norway, and the U.K. issued warnings against prescribing children puberty blockers and hormone drugs.
A request filed under the Freedom of Information Act earlier this year resulted in an admission from Rachel Levine, assistant secretary of the U.S. Department of Health and Human Services, that his claims that gender transition procedures for children are “lifesaving” and “necessary” were based entirely on a two-page document citing a single study conducted by an LGBT activist organization.
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Australia: Suicide of 10-year-old Aboriginal boy in the care of Aboriginal relatives described as 'unimaginable'
The "stolen generation" myth put about by Leftist historians means that social workers trying to help a neglected Aboriginal child are obliged to rehouse the child with other Aborigines, who are often as feckless as the neglectful families.
If the old custom of fostering the endangered child into a white family had been followed, the boy would almost certainly still be alive. Attention-seeking Leftist lies can kill
A suicide prevention advocate says a 10-year-old Indigenous boy who took his own life in Western Australia is the youngest child to have died by suicide in child protection on record.
The boy, who cannot be named, died on Saturday night while living with a relative while under the care of WA's Department of Communities.
Veteran advocate Gerry Georgatos said there were "high categorical risks" of suicide in child protection.
"One so young it should be unimaginable, particularly in care under the state," Mr Georgatos said. "He's the youngest recorded suicide in child protection custody in any form of out-of-home care."
The boy was found by his carer in the back room of the home.
The 10-year-old's parents had not seen him for eight months and had been working towards being reunited with him.
Mr Georgatos has been offering support to the boy's family in the wake of the tragedy. He said the family was "distressed" and "devastated". "The father described to me that he just collapsed in front of the police, the mother was distraught. They couldn't believe it," he said.
The boy has been in child protection custody for several years, according to Mr Georgatos.
"There are laws that prohibit a family from speaking out. And that is actually a tragedy in itself. Because the families want to speak, they want to say his name," Ms Krakouer said.
"He's this beautiful little boy, 10 years old." She said the "angelic-faced boy" was taken into state care in 2020.
"The father and the mother, they couldn't pay their rent. It is a poverty narrative across the country," Ms Krakouer said.
Ms Krakouer urged the Department of Child Protection to give custody of the parents' remaining children back to them.
"In terms of the mum and dad, they're beautiful, strong, solid people. They're kind," she said. "There is no reason for them not to have their children returned."
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My other blogs. Main ones below:
http://dissectleft.blogspot.com (DISSECTING LEFTISM)
http://edwatch.blogspot.com (EDUCATION WATCH)
http://antigreen.blogspot.com (GREENIE WATCH)
http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)
http://snorphty.blogspot.com/ (TONGUE-TIED)
http://jonjayray.com/blogall.html More blogs
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Kristina Pimenova, once said to be the most beautiful girl in the world. Note blue eyes and blonde hair
Bliss: What every woman wants: to feel safe and secure in the arms of her man. Robert Irwin and Rorie Buckey. See
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